nk 252 has been researched along with (1S,2R)-2-[[(1S)-1-[(1,3-dioxo-2-isoindolyl)methyl]-3,4-dihydro-1H-isoquinolin-2-yl]-oxomethyl]-1-cyclohexanecarboxylic acid in 2 studies
Studies (nk 252) | Trials (nk 252) | Recent Studies (post-2010) (nk 252) | Studies ((1S,2R)-2-[[(1S)-1-[(1,3-dioxo-2-isoindolyl)methyl]-3,4-dihydro-1H-isoquinolin-2-yl]-oxomethyl]-1-cyclohexanecarboxylic acid) | Trials ((1S,2R)-2-[[(1S)-1-[(1,3-dioxo-2-isoindolyl)methyl]-3,4-dihydro-1H-isoquinolin-2-yl]-oxomethyl]-1-cyclohexanecarboxylic acid) | Recent Studies (post-2010) ((1S,2R)-2-[[(1S)-1-[(1,3-dioxo-2-isoindolyl)methyl]-3,4-dihydro-1H-isoquinolin-2-yl]-oxomethyl]-1-cyclohexanecarboxylic acid) |
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11 | 0 | 8 | 13 | 0 | 13 |
Protein | Taxonomy | nk 252 (IC50) | (1S,2R)-2-[[(1S)-1-[(1,3-dioxo-2-isoindolyl)methyl]-3,4-dihydro-1H-isoquinolin-2-yl]-oxomethyl]-1-cyclohexanecarboxylic acid (IC50) |
---|---|---|---|
Kelch-like ECH-associated protein 1 | Homo sapiens (human) | 1.798 | |
Nuclear factor erythroid 2-related factor 2 | Homo sapiens (human) | 2.65 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 2 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Bach, A; Pallesen, JS; Tran, KT | 1 |
Aguayo-Orozco, A; Bach, A; Baig, A; Carmona, RMC; Garcia, AD; Narayanan, D; Pallesen, JS; Solbak, SMØ; Tran, KT; Zang, J | 1 |
2 other study(ies) available for nk 252 and (1S,2R)-2-[[(1S)-1-[(1,3-dioxo-2-isoindolyl)methyl]-3,4-dihydro-1H-isoquinolin-2-yl]-oxomethyl]-1-cyclohexanecarboxylic acid
Article | Year |
---|---|
Non-covalent Small-Molecule Kelch-like ECH-Associated Protein 1-Nuclear Factor Erythroid 2-Related Factor 2 (Keap1-Nrf2) Inhibitors and Their Potential for Targeting Central Nervous System Diseases.
Topics: Central Nervous System Diseases; Humans; Kelch-Like ECH-Associated Protein 1; Molecular Structure; NF-E2-Related Factor 2; Protein Interaction Domains and Motifs; Small Molecule Libraries | 2018 |
A Comparative Assessment Study of Known Small-Molecule Keap1-Nrf2 Protein-Protein Interaction Inhibitors: Chemical Synthesis, Binding Properties, and Cellular Activity.
Topics: Cell Line, Tumor; Dose-Response Relationship, Drug; Humans; Kelch-Like ECH-Associated Protein 1; Models, Molecular; Molecular Structure; NF-E2-Related Factor 2; Protein Binding; Small Molecule Libraries; Structure-Activity Relationship; Surface Plasmon Resonance | 2019 |